Caterina Bendotti Selected Research

RNS60

1/2023	Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double-blind, placebo-controlled trial.
1/2019	A pilot trial of RNS60 in amyotrophic lateral sclerosis.
3/2018	RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue.

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Caterina Bendotti Research Topics

Disease

38	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2023 - 03/2003
21	Disease Progression 04/2023 - 01/2009
7	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 08/2004
6	Inflammation (Inflammations) 01/2023 - 10/2012
5	Neuroinflammatory Diseases 01/2023 - 01/2017
4	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2019 - 01/2006
3	Atrophy 03/2023 - 01/2020
3	Muscular Atrophy (Muscle Atrophy) 01/2022 - 02/2012
2	Neoplasms (Cancer) 01/2022 - 01/2018
2	Demyelinating Diseases (Demyelinating Disease) 03/2018 - 10/2012
2	Mitochondrial Diseases (Mitochondrial Disease) 02/2007 - 05/2005
1	Paralysis (Palsy) 01/2022
1	Astrocytoma (Pilocytic Astrocytoma) 01/2020
1	Gliosis 01/2019
1	Acute-Phase Reaction 11/2018
1	Colonic Neoplasms (Colon Cancer) 01/2018
1	Cachexia 01/2018
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 04/2015
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 10/2012
1	Sciatic Neuropathy (Lesion of Sciatic Nerve) 08/2011
1	Wallerian Degeneration 08/2011
1	Nervous System Diseases (Neurological Disorders) 01/2011
1	Hypertrophy 01/2007
1	Substance-Related Disorders (Drug Abuse) 11/2004
1	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 11/2002

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 01/2023 - 04/2005
8	Superoxide Dismutase-1IBA 01/2017 - 10/2003
6	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2011
3	RNS60IBA 01/2023 - 03/2018
3	Superoxide DismutaseIBA 05/2013 - 07/2006
2	Cholinergic ReceptorsIBA 04/2023 - 03/2023
2	ChemokinesIBA 12/2020 - 02/2011
2	AntioxidantsIBA 03/2018 - 08/2004
2	CytokinesIBA 01/2017 - 02/2011
2	AMPA Receptors (AMPA Receptor)IBA 01/2017 - 01/2006
2	Cyclophilin AIBA 01/2017 - 01/2011
2	UbiquitinIBA 05/2012 - 01/2009
2	Proteasome Endopeptidase Complex (Proteasome)IBA 05/2012 - 01/2009
2	EnzymesIBA 08/2011 - 08/2004
2	Protein Isoforms (Isoforms)IBA 08/2011 - 03/2003
2	Small Heat-Shock ProteinsIBA 10/2010 - 09/2010
2	Glutamic Acid (Glutamate)FDA Link 01/2006 - 01/2004
1	Interleukin-10 (Interleukin 10)IBA 01/2023
1	Small Interfering RNA (siRNA)IBA 01/2022
1	Adenosine Triphosphatases (ATPase)IBA 01/2022
1	Disulfiram (Antabuse)FDA Link 01/2022
1	Muscle Proteins (Muscle Protein)IBA 01/2022
1	Nuclear Proteins (Protein, Nuclear)IBA 01/2022
1	coomassie Brilliant BlueIBA 09/2021
1	Purinergic P2X7 ReceptorsIBA 09/2021
1	Creatine Kinase (Creatine Phosphokinase)IBA 01/2020
1	Transfer RNA (tRNA)IBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	Ribonucleases (Ribonuclease)IBA 01/2020
1	Naphazoline (All Clear)FDA LinkGeneric 01/2020
1	angiogeninIBA 01/2020
1	Protein AggregatesIBA 01/2019
1	Neuroprotective AgentsIBA 01/2019
1	ProteomeIBA 11/2018
1	Contrast MediaIBA 01/2018
1	CalciumIBA 01/2017
1	Type II Tumor Necrosis Factor ReceptorsIBA 01/2017
1	talampanelIBA 01/2017
1	cis-trans-IsomerasesIBA 01/2017
1	Amino Acids FDA Link 05/2016
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2015
1	CopperIBA 05/2013
1	ZincIBA 05/2013
1	Eicosapentaenoic AcidIBA 01/2013
1	coenzyme Q10 (CoQ10)IBA 01/2013
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2013
1	AlbuminsIBA 11/2012
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 11/2012
1	Phosphatidylinositols (Phosphatidylinositol)IBA 11/2012
1	Protein Kinases (Protein Kinase)IBA 11/2012
1	Citrate (si)-Synthase (Synthase, Citrate)IBA 11/2012
1	Claudin-5IBA 10/2012
1	OccludinIBA 10/2012
1	Caveolin 1IBA 10/2012
1	MyogeninIBA 02/2012
1	Nandrolone (Nortestosterone)IBA 02/2012
1	Transforming Growth Factors (Transforming Growth Factor)IBA 02/2012
1	Anabolic Androgenic SteroidsIBA 02/2012
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 02/2011
1	HomocysteineIBA 01/2010
1	Lithium Carbonate (Eskalith)FDA LinkGeneric 08/2009
1	HLA-DR Antigens (HLA-DR)IBA 05/2009
1	Ubiquitinated ProteinsIBA 01/2009
1	HMGB1 Protein (HMG1)IBA 01/2007
1	Ethacrynic Acid (Etacrynic Acid)FDA Link 05/2005
1	Mutant Proteins (Protein, Mutant)IBA 05/2005
1	RotenoneIBA 05/2005
1	Free RadicalsIBA 05/2005
1	Glutathione (Reduced Glutathione)IBA 05/2005
1	GAP-43 Protein (GAP 43 Protein)IBA 11/2004
1	Messenger RNA (mRNA)IBA 03/2003

Therapy/Procedure

6	Therapeutics 01/2023 - 01/2011
4	Muscle Denervation 03/2023 - 10/2016
3	Denervation 01/2022 - 01/2020
2	Injections 01/2023 - 12/2017